Bioactivity evaluation of least explored traditionally acclaimed medicinally potent herb Nanorrhinum ramosissimum(Wall.) Betsche

Present study analysed the therapeutic potential of traditionally acclaimed medicinal herb Nanorrhinum ramosissimum, using plant parts extracted with different solvents (10 mg/mL). Shoot extracts exhibited comparatively better antimicrobial properties, in comparison to root extracts. Total phenolic content was estimated, ascertain its dependency on antioxidant properties Antioxidant assay revealed promising results IC50 value standard ascorbic acid (52.2±0.07 µg/mL), for methanolic shoot (61.07±0.53 µg/mL and 64.33±0.33 µg/mL) (76.705±0.12 89.73±0.28 µg/ mL) vivo vitro regenerants respectively. Correlation coefficient R2 values ranged between 0.90-0.95, indicating a positive correlation contents activity. Plant were also able inhibit DNA oxidative damage again their antioxidative potential. Antidiabetic confirmed by alpha amylase inhibition where (invivo, vitro) best (54.42±0.16 µg/mL, 66.09±0.12 metformin (41.92±0.08 µg/mL). Ethanolic roots (in vitro, invivo) relative (88.97±0.32µg/mL,96.63±0.44 that had property; thus proving herb’s bioactive prospective source curing various ailments.